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Chenglong Zhao, University of Dayton

Time:
3:30pm
Location:
Virtual seminar

Single molecule imaging reveals conformational dynamics of synaptic proteins

Host: Peng Li

Prof. Chenlong Zhao

Department of Physics 

Department of Electro-Optics and Photonics

The University of Dayton 

Zhao

In this talk, I will introduce an opto-thermomechanical (OTM) nanoprinting method that allows us not only to additively print nanostructures with sub-100 nm accuracy but also to correct printing errors for nanorepairing under ambient conditions. In addition, I will introduce an acoustofluidic scanning nanoscope that can simultaneously achieve high resolution with a large field of view. Optical imaging with nanoscale resolution and a large field of view is challenging to achieve using a conventional microscope. An objective lens with a low numerical aperture (NA) has a large field of view but poor resolution. In contrast, a high NA objective lens will have a  higher resolution but reduced field of view. The acoustofluidic scanning nanoscope is developed in an effort to close the gap between these trade-offs, which can achieve subdiffraction-limit resolution and a large field of view simultaneously.