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Glen P. Jackson, Ph.D.

Ming Hsieh Distinguished Professor of Forensic and Investigative Science

Chemistry Joint Professor

Jackson Group Website

About

Ph.D., West Virginia University

Our long-term goal is to catalyze the progress of biomedical, analytical and forensic research through the development of mass spectrometric instrumentation. We currently have several major projects under way:

  1. New ways of fragmenting gas-phase bio-ions, including peptides and oligosaccharides, in tandem mass spectrometers using kiloelectronvolt helium ions. We use the term charge transfer dissociation (CTD-MS) to describe the mechanism of activation.  (example publication) 
  2. New forensic applications of isotope ratio mass spectrometry, including hair, nails and blow flies. (example publication) 
  3. Understanding the mass spectrometric fragmentation behavior of novel psychoactive substances (NPSs).  (example publication) 
  4. Development of new algorithms for mass spectral comparisons. 
  5. Experimental and theoretical approaches to understand the evaporation of ignitable liquids at elevated temperatures (e.g. 200 °C).  (example publication) 

See all our recent publications.

Teaching Area

Forensic chemistry

Courses Offered

  • FIS 660 Advanced Forensic Chemistry
  • FIS 460/1 Seized Drugs Analysis/Lab
  • FIS 451/2 Arson and Explosives Analysis/Lab 

Publications

M. K. Santos, G. B. Walber, L. J. Danielli, T. Kreutz, K.Soares, K. C. Mariotti, M. Ritter, L. E. Arroyo, G. P. Jackson, R. P. Limberger, “Evaluation of the Presence of 1,3-Dimethylamylamine in Pelargonium  Leaves and Essential Oils by Mass Spectrometric and Chromatographic Methods,” Chromatographia , 2019 , 82(5), 875-883.    View at Springer

J. T. Davidson, G. P. Jackson, “The Differentiation of 2,5-dimethoxy-N-(N-methoxy-benzyl)phenethylamine (NBOMe) Isomers Using GC Retention Indices and Multivariate Analysis of Ion Abundances in Electron Ionization Mass Spectra,”  Forens. Chem.2019, 14, 100160.  View at Elsevier.

M. P. V. Matos, G. P. Jackson, “Isotope Ratio Mass Spectrometry in Forensic Science Applications,” Forens. Chem., 2019, 13, 100154. View at Elsevier.

M. P. V. Matos, K. I. Konstantynova, R. M. Mohr, G. P. Jackson, “Analysis of the 13C Isotope Ratios of Amino Acids in the Larvae, Pupae, and Adult Stages of Calliphora vicina Blow Flies and their Carrion Food Sources,” Anal. BioAnal. Chem.,  2018, 410, 7943-7954. View at Springer

J. T. Davidson, B. J. Lum, G. Nano, G. P. Jackson, “Comparison of Measured and Recommended Acceptance Criteria for the Analysis of Seized Drugs using Gas Chromatography-Mass Spectrometry (GC-MS),” Forens. Chem., 2018, 10: 15-26. View at Elsevier

M. K. Santos, E. Gleco, J. T. Davidson, D. B. J. Neves, G. P. Jackson, R. P. Limberger, L. E. Arroyo, “DART-MS/MS Screening for the Determination of 1,3-Dimethylamylamine (DMAA) and Undeclared Stimulants in Seized Dietary Supplements from Brazil,” Forens. Chem., 2018, 8, 134-145. View at Elsevier

S. Khodjaniyazova, M. Nazari, M. P. V. Matos, G. P. Jackson, D. C. Muddiman, “Characterization of the Spectral Accuracy of an Orbitrap Mass Analyzer using Isotope Ratio Mass Spectrometry,” Anal. Chem., 2018, 90, 1897-1906. View at ACS 

P. Li, I. C. Kreft, G. P. Jackson, “Top-Down Charge Transfer Dissociation (CTD) of Gas-Phase Insulin: Evidence of a One-Step, Two-Electron Oxidation Mechanism,” J. Am. Soc. Mass Spectrom. (Special Focus Section on 32nd Asilomar Conference, Novel Instrumentation in MS and Ion Mobility), 2018, 29(2) 284-296. View at Springer 

D. Ropartz, P. Li, G. P. Jackson, H. Rogniaux, “Negative Polarity Helium Charge Transfer Dissociation Tandem Mass Spectrometry: Radical-Initiated Fragmentation of Complex Polysulfated Anions,” Anal.Chem., 2017, 89(7), 3824-3828. View at ACS

H. L. Birks, A. R. Cochran, T. J. Williams, G. P. Jackson, “The Surprising Effect of Temperature on the Weathering of Gasoline,” Forens. Chem., 2017, 4, 32-40. View at Elsevier

P. Li, G. P. Jackson, “Charge Transfer Dissociation (CTD) of Phosphocholines: Gas-Phase Ion/Ion Reactions Between Helium Cations and Phospholipid Cations,” J. Mass Spectrom., 2017, 52 (5), 271-282. View at Wiley 

P. Li, G. P. Jackson, “Charge Transfer Dissociation (CTD) Mass Spectrometry of Peptide Cations: Study of Charge State Effects and Side-Chain Losses,” J. Am. Soc. Mass Spectrom. (Special Focus Section in Honor of Scott McLuckey, recipient of the 2016 ASMS Award for a Distinguished Contribution in Mass Spectrometry), 2017, 28, 1271-1281. View at Springer 

G. P. Jackson “Error Terror in Forensic Science: When Spectroscopy Meets the Courts,” Spectroscopy, 2016, 31(11), 12-16. Spectroscopy Online 

D. Ropartz, P. Li, M. Fanuel, A. Giuliani, H. Rogniaux, G. P. Jackson, “Charge Transfer Dissociation of Complex Oligosaccharides: Comparison with Collision-Induced Dissociation and Extreme Ultraviolet Dissociative Photoionization,” J. Am. Soc. Mass Spectrom., 2016, 27, 1614-1619. View at Springer 

P. Li, W. D. Hoffmann and G. P. Jackson “Multistage Mass Spectrometry of Phospholipids using Collision-Induced Dissociation (CID) and Metastable Atom-Activated Dissociation (MAD),” Int. J. Mass Spectrom.,  2016,  403, 1-7.    View at Elsevier

M. Zhang, N. A. Kruse, J. R. Bowman, G. P. Jackson “Field Analysis of Polychlorinated Biphenyls (PCBs) in Soil using a Portable Solid Phase Microextrction (SPME) and Gas Chromatograph/Mass Spectrometry System,” Appl. Spectrosc. (Special Edition on Mobile Spectrometers), 2016,  70(5), 785-793.  View at Sage 

F. Huelsemann, C. Lehn, S. Schneiders, G. P. Jackson, S. Hill, A. Rossmann, N. Scheid, P. J. H. Dunn, U. Flenker, W. Schänzer “Global Spatial Distributions of Nitrogen and Carbon Stable Isotope Ratios of Modern Human Hair,” Rapid Commun. Mass Spectrom., 2015,29, 2111-2121.  View at Wiley 

R. E. Deimler, M. Sander, G. P. Jackson “Radical-Induced Fragmentation of Phospholipid Cations using Metastable Atom-Activated Dissociation Mass Spectrometry (MAD-MS),” Int. J. Mass Spectrom. (Special Edition on Biological Radicals),  2015, 390, 178-186. View at Elsevier 

A. H. B. Rashaid, P. B. Harrington, G. P. Jackson “Profiling Amino Acids of Jordanian Scalp Hair as a Tool for Diabetes Mellitus Diagnosis: A Pilot Study,” Anal. Chem., 2015, 87, 7078-7084. View at ACS 

W. D. Hoffmann and G. P. Jackson “Forensic Mass Spectrometry,” Ann. Rev. Anal. Chem., 2015, 8, 419-440. 
A. H. B. Rashaid, P. B. Harrington and G. P. Jackson “Amino Acid Composition of Human Scalp Hair as a Biometric Classifier and Investigative Lead,” Anal. Methods, 2015, 7, 1707-1718. View at RSC 

W. D. Hoffmann, F. Jin, G. P. Jackson “Performance Evaluation of a Loeb-Eiber Mass Filter at 1 Torr,” J. Am. Soc. Mass Spectrom. (Focus on Harsh Environment and Field-Portable Mass Spectrometry), 2015, 26(2), 286-291. View at Springer 

G. P. Jackson, Y. An. K. I. Konstantynova, A. H. B. Rashaid “Biometrics from the Carbon Isotope Ratio Analysis of Amino Acids in Human Hair,” Sci. Justice (FIRMS 2013 Special Edition), 2015, 55, 43-50. View at Elsevier 

Citations on Google Scholar